The Genetic Architecture of Multiple Myeloma
نویسندگان
چکیده
منابع مشابه
Treatment of Multiple Myeloma
Les traitements classiques de myelome multiple et les schemas differents proposes ont ete mis en revue. La poly chimiotherapie de la maladie avec une com-binaison de cyclophosphamide, B.C.N.U. Alkeran, Perdnisone et Vincristine a donnee une meilleur Resultat ceci surtout dans les formes graves et rapidement progressive de la maladie. D'autres sehemas therapeutiques sont en cours.
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Multiple myeloma (MM) is a human cancer of malignant plasma cells. Recent genomic studies have started to catalog all the genetic alterations in selected panels of MM samples, and, within a short period of time, the large majority of MM-associated genetic and transcriptional alterations will have been identified. These recent insights, on one hand, indicate that MMs can harbor extensive clonal ...
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Multiple myeloma is a monoclonal malignant proliferation of plasma cells. The disease is more frequent in men, and the average age of patients at the time of diagnosis of the disease is about 60 years. Solitary myeloma may be the first manifestation of the disseminated form of multiple myeloma, which is characterized by multiple skeletal lesions, general metabolic alterations, impairment of ren...
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Multiple myeloma is a malignant proliferation of monoclonal plasma cells leading to clinical features that include hypercalcaemia, renal dysfunction, anaemia, and bone disease (frequently referred to by the acronymCRAB) which represent evidence of end organ failure. Recent evidence has revealed myeloma to be a highly heterogeneous disease composed of multiple molecularly-defined subtypes each w...
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ژورنال
عنوان ژورنال: Advances in Hematology
سال: 2014
ISSN: 1687-9104,1687-9112
DOI: 10.1155/2014/864058